SAPHOsyndromeSAPHO
SAPHOsyndromeincludesavarietyofinflammatorybonedisordersthatmaybeassociatedwithskinchanges.Thesediseasessharesomeclinical,radiologic,andpathologiccharacteristics.
Anentityinitiallyknownaschronicrecurrentmultifocalosteomyelitis(CRMO)wasfirstdescribedin.Subsequently,in,severalcasesofCRMOwereassociatedwithblistersonthepalmsandsoles(palmoplantarpustulosis).Sincethen,anumberofassociationsbetweenskinconditionsandosteoarticulardisordershavebeenreportedunderavarietyofnames,includingsternocostoclavicularhyperostosis,pustuloticarthro-osteitis,andacne-associatedspondyloarthropathy.ThetermSAPHO(synovitis,acne,pustulosis,hyperostosis,osteitis)wascoinedintorepresentthisspectrumofinflammatorybonedisordersthatmayormaynotbeassociatedwithdermatologicpathology.
Radiologicfindings
Anteriorchestwall(most鍖椾含娌荤枟鐧界櫆椋庡幓鍝鍖椾含鐧界櫆椋庝笓瀹?
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